October 31, 2025

All-nighters hit your brain’s spin cycle

Attention lapses due to sleep deprivation due to flushing fluid from brain

MIT says your brain runs a wash cycle when you’re exhausted — and the internet says go to bed

TLDR: MIT found your brain’s cleaning fluid surges while you’re awake after little sleep, causing attention slip-ups. Commenters rallied for bedtime, joked about “dolphin brain” hacks, debated power naps, and eulogized all-nighters—collectively warning that sleep beats cramming if you want your focus (and sanity) to survive.

MIT just dropped a wild brain reveal: when you pull an all-nighter, your mind hits a surprise “wash cycle.” In lab tests, people who missed sleep had waves of clear brain-cushioning fluid (cerebrospinal fluid) rush in and out—housekeeping that usually happens during sleep—and their attention crashed during those flushes. Think brain laundry, at the worst possible time. The study appears in Nature Neuroscience via the MIT team.

The comments section? A pillow fight. Sleep evangelists cheered, with one praising healthy shut‑eye and even light exercise for the brain’s cleaning system. Parents rolled in with dark comedy—one wondered if having kids accelerates brain fog. The nap squad demanded answers: will a 30‑minute power nap reset this, and can we “tell the brain to hold the flushing” until then? Meanwhile, a “dolphin mode” crowd bragged about putting unused brain parts to sleep on command, prompting gasps when one described migraine auras where parts of vision vanish.

Students caught strays as the thread held a funeral for all-nighters—“RIP to the 24‑hour cram.” Bottom line: the internet agrees on one thing—sleep wins—but the battle lines are drawn between nap hackers, exhausted parents, and legendary crammers desperate for one more shortcut.

Key Points

  • MIT study links attention lapses during sleep deprivation to waves of CSF flushing out of the brain.
  • CSF flushing normally occurs during sleep to clear accumulated waste and support brain health.
  • Researchers tested 26 volunteers in both sleep-deprived and well-rested states using EEG and modified fMRI.
  • Participants performed visual and auditory attention tasks; sleep-deprived individuals had slower responses and missed stimuli.
  • Momentary attention failures coincided with physiological changes, notably CSF flux out of the brain, and the study was published in Nature Neuroscience.

Hottest takes

"I am wondering if there is a correlation between dementia and having kids." — cdelsolar
"My brain is like that of a dolphin now." — jongjong
"Rest in peace to all the college dudes covering the whole syllabus within 24 hours of the exam" — paglaghoda
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